The EREG Polyclonal Antibody (CAB16372) is a valuable tool for research involving EREG, a cell signaling molecule known for its role in promoting cell growth and proliferation. This antibody, raised in rabbits, is highly specific for detecting EREG in human samples and has been validated for use in a variety of applications, particularly in immunohistochemistry and ELISA.EREG, or epiregulin, is a member of the epidermal growth factor (EGF) family and has been implicated in various physiological processes, including wound healing, tissue regeneration, and tumorigenesis. Its ability to activate the EGF receptor pathway makes it an important target for studies in cancer research, as well as potentially other diseases involving abnormal cell growth.
By using the EREG Polyclonal Antibody, researchers can accurately detect and quantify EREG expression in different cell types and tissues, providing valuable insights into its functions and potential therapeutic applications. This antibody is ideal for studies aiming to understand the role of EREG in various biological processes, ultimately contributing to the development of novel treatments for EREG-related diseases.
Product Name:
EREG Rabbit Polyclonal Antibody
SKU:
CAB16372
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 70-169 of human EREG (NP_001423.1).
Cell membrane, Secreted, Single-pass type I membrane protein, extracellular space.
Calculated MW:
19kDa
Observed MW:
17kDa/19kDa
This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). The encoded protein may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, the encoded protein may promote the progression of cancers of various human tissues.
Purification Method:
Affinity purification
Gene ID:
2069
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using EREG Rabbit pAb (CAB16372) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
