The ERCC6L2 Polyclonal Antibody (CAB13144) is a vital tool for research involving the ERCC6L2 protein, a key player in DNA repair processes. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. It effectively binds to ERCC6L2, allowing for precise detection and analysis in a variety of cell types, making it an ideal choice for studies in genetics and cancer research.ERCC6L2, also known as DNA excision repair protein ERCC-6-like 2, plays a crucial role in maintaining genomic stability by repairing DNA damage.
Dysregulation of ERCC6L2 has been linked to various genetic disorders and cancers, highlighting its importance in cellular health and disease prevention. Understanding the function of ERCC6L2 is essential for developing targeted therapies that can enhance DNA repair mechanisms and prevent the accumulation of mutations that lead to disease development.
Product Name:
ERCC6L2 Rabbit Polyclonal Antibody
SKU:
CAB13144
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1262-1561 of human ERCC6L2 (NP_064592.2).
This gene encodes a member of the Snf2 family of helicase-like proteins. The encoded protein may play a role in DNA repair and mitochondrial function. Mutations in this gene have been associated with bone marrow failure syndrome 2. Alternatively spliced transcript variants that encode different protein isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
375748
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ERCC6L2 Rabbit pAb (CAB13144) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
