ERCC6 Rabbit Polyclonal Antibody (CAB18211)
- SKU:
- CAB18211
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | ERCC6 Rabbit Polyclonal Antibody |
SKU: | CAB18211 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 700-800 of human ERCC6 (NP_000115.1). |
Sequence: | LPVF MEQF SVPI TMGG YSNA SPVQ VKTA YKCA CVLR DTIN PYLL RRMK SDVK MSLS LPDK NEQV LFCR LTDE QHKV YQNF VDSK EVYR ILNG EMQI FSGL I |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | CSB; CKN2; COFS; ARMD5; COFS1; POF11; RAD26; UVSS1; CSB-PGBD3; ERCC6 |
Positive Sample: | 293T,A-549,Mouse thymus,Rat testis |
Cellular Localization: | B-WICH complex, nucleolus, nucleoplasm, nucleus, transcription elongation factor complex |
Calculated MW: | 168kDa |
Observed MW: | 168kDa |
This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Alternative splicing occurs between a splice site from exon 5 of this gene to the 3' splice site upstream of the open reading frame (ORF) of the adjacent gene, piggyback-derived-3 (GeneID:267004), which activates the alternative polyadenylation site downstream of the piggyback-derived-3 ORF. The resulting transcripts encode a fusion protein that shares sequence with the product of each individual gene.
Purification Method: | Affinity purification |
Gene ID: | 2074 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |