ERCC4 Rabbit Polyclonal Antibody (CAB8119)
- SKU:
- CAB8119
- Product Type:
- Antibody
- Applications:
- WB
- IP
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | ERCC4 Rabbit Polyclonal Antibody |
SKU: | CAB8119 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 513-782 of human ERCC4 (NP_005227.1). |
Sequence: | GYRR EISS SPES CPEE IKHE EFDV NLSS DAAF GILK EPLT IIHP LLGC SDPY ALTR VLHE VEPR YVVL YDAE LTFV RQLE IYRA SRPG KPLR VYFL IYGG STEE QRYL TALR KEKE AFEK LIRE KASM VVPE EREG RDET NLDL VRGT ASAD VSTD TRKA GGQE QNGT QQSI VVDM REFR SELP SLIH RRGI DIEP VTLE VGDY ILTP EMCV ERKS ISDL IGSL NNGR LYSQ CISM SRYY KRPV LLIE FDPS KPFS LTSR GALF QEIS SN |
Tested Applications: | WB IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | XPF; RAD1; FANCQ; XFEPS; ERCC11; ERCC4 |
Positive Sample: | U-251MG,HT-1080 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 104kDa |
Observed MW: | 120kDa |
The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).
Purification Method: | Affinity purification |
Gene ID: | 2072 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |