The ERC1 Polyclonal Antibody (CAB9509) is a valuable tool for researchers studying ERC1, a protein involved in regulating cell migration and organization in various cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to ERC1, researchers can effectively detect and analyze this protein in different cell types, allowing for detailed investigation in fields such as cell biology and cancer research.ERC1, also known as ELKS/RAB6-interacting/CAST family member 1, plays a crucial role in organizing the cytoskeleton and facilitating intracellular trafficking, making it a key player in cellular function and dynamics.
Its involvement in cell migration and organization highlights its significance in processes such as wound healing, neuronal development, and cancer metastasis. Research on ERC1 holds great potential for uncovering new insights into cellular mechanisms and developing targeted therapies for various diseases.By utilizing the ERC1 Polyclonal Antibody (CAB9509), researchers can delve deeper into the functions and interactions of ERC1, ultimately advancing our understanding of cellular processes and potentially uncovering novel therapeutic targets for various diseases.
Product Name:
ERC1 Rabbit Polyclonal Antibody
SKU:
CAB9509
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 700-850 of human ERC1 (NP_829884.1).
The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
23085
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ERC1 Rabbit pAb (CAB9509) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
