ERAS Antibody (PACO33396)
- SKU:
- PACO33396
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
ERAS Antibody (PACO33396)
The ERAS Antibody (PAC033396) is a polyclonal antibody specifically designed for research involving ERAS, a protein known for its role in regulating the Ras signaling pathway. This antibody, produced using rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the ERAS protein, this antibody enables the detection and analysis of ERAS in various cell types, making it a valuable tool for studies in signal transduction and cancer research.ERAS, a member of the Ras family of small GTPases, is involved in regulating cell growth, proliferation, and differentiation.
Dysregulation of the Ras signaling pathway, including ERAS, has been implicated in various cancers and developmental disorders. By understanding the function of ERAS, researchers can gain insights into the molecular mechanisms underlying these conditions and potentially identify new therapeutic targets.The ERAS Antibody (PAC033396) is a vital tool for researchers focused on studying the role of ERAS in cellular signaling and disease development. Its high specificity and reactivity make it an ideal choice for experiments aimed at unraveling the complex functions of ERAS in health and disease.
| Antibody Name: | ERAS Antibody (PACO33396) |
| Antibody SKU: | PACO33396 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human GTPase ERas protein (3-230AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: ERAS antibody at 2µg/ml + 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 26 kDa Observed band size: 26 kDa . |
| Background: | Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the tumor-like growth properties of embryonic stem cells. |
| Synonyms: | GTPase ERas (E-Ras) (Embryonic stem cell-expressed Ras), ERAS, HRAS2 HRASP |
| UniProt Protein Function: | ERas: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the tumor-like growth properties of embryonic stem cells. Belongs to the small GTPase superfamily. Ras family.Protein type: G protein, monomeric, Ras; G protein, monomeric; G proteinChromosomal Location of Human Ortholog: Xp11.23 |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance. [provided by RefSeq, Dec 2012] |
| UniProt Code: | Q7Z444 |
| NCBI GenInfo Identifier: | 74723320 |
| NCBI Gene ID: | 3266 |
| NCBI Accession: | Q7Z444.1 |
| UniProt Secondary Accession: | Q7Z444 |
| UniProt Related Accession: | Q7Z444 |
| Molecular Weight: | 25,287 Da |
| NCBI Full Name: | GTPase ERas |
| NCBI Synonym Full Names: | ES cell expressed Ras |
| NCBI Official Symbol: | ERASÂ Â |
| NCBI Official Synonym Symbols: | HRAS2; HRASPÂ Â |
| NCBI Protein Information: | GTPase ERas |
| UniProt Protein Name: | GTPase ERas |
| UniProt Synonym Protein Names: | Embryonic stem cell-expressed Ras |
| Protein Family: | GTPase |
| UniProt Gene Name: | ERASÂ Â |
| UniProt Entry Name: | RASE_HUMAN |
| Antibodies |
| ERAS Antibody (PACO04072) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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