The EPSTI1 Polyclonal Antibody (PACO16263) is a valuable tool for researchers studying EPSTI1, a protein involved in immune response regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blotting. By specifically binding to the EPSTI1 protein, this antibody enables precise detection and analysis in different cell types, making it perfect for studies in immunology and cancer research.
EPSTI1, also known as an interferon-stimulated gene, plays a crucial role in modulating immune responses by regulating various immune pathways. Its involvement in immune function makes it a promising target for research on diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Delving into the functions of EPSTI1 is essential for developing treatments that manipulate immune responses effectively in these disease settings.
Antibody Name:
EPSTI1 Antibody (PACO16263)
Antibody SKU:
PACO16263
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:
Human
Immunogen:
Fusion protein of human EPSTI1
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human placenta tissue, Primary antibody: PACO16263(EPSTI1 Antibody) at dilution 1/2000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes.
Background:
EPSTI1 (Epithelial-stromal interaction protein 1), also known as BRESI1, is a 318 amino acid, protein that is highly expressed in spleen, placenta, small intestine, liver, kidney, thymus, testis and salivary gland. Existing as three isoforms that are formed due to alternative splicing events, EPSTI1 is weakly expressed in normal breast tissue, but is heavily up-regulated in breast carcinoma, suggesting an important role for EPSTI1 in tumor formation and/or progression. Additionally, EPSTI1 is found in blood cells from systemic lupus erythematosus (SLE)-afflicted patients, implicating EPSTI1 as a potential protein involved in SLE.
Synonyms:
epithelial stromal interaction 1
UniProt Protein Function:
EPSTI1: 3 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 13q13.3
