The EPS8L3 Polyclonal Antibody (PAC023759) is a vital tool for researchers studying EPS8L3, a protein involved in cellular signaling pathways and gene regulation. This rabbit-raised antibody is highly specific to human EPS8L3 and has been validated for use in Western blot applications, providing accurate detection and analysis of the protein in various cell types.EPS8L3 is known to play a crucial role in cell migration, proliferation, and invasion, making it a target of interest in cancer research and developmental biology. By understanding the function of EPS8L3, researchers can gain insights into mechanisms underlying tumor growth and metastasis, as well as cellular processes involved in tissue development and repair.
With its high specificity and reliability in detecting EPS8L3, the PAC023759 antibody is a valuable tool for studying the functions of this protein in a variety of biological contexts. Its application extends to areas such as oncology, cell biology, and developmental research, providing researchers with a versatile tool for exploring the diverse roles of EPS8L3 in human health and disease.
Synthesized peptide derived from internal of human ES8L3.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from Cos7 cells and K562 cells, using ES8L3 antiobdy.
Immunofluorescence analysis of HeLa cells, using ES8L3 antibody.
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using ES8L3 antibody.
Background:
This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. Alternatively spliced transcript variants encoding different isoforms exist.
Synonyms:
Epidermal growth factor receptor pathway substrate 8-related protein 3; EPS8-like protein 3;
UniProt Protein Function:
EPS8L3: a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. Alternatively spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Jul 2008]Protein type: Unknown functionChromosomal Location of Human Ortholog: 1p13.3
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. Alternatively spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Jul 2008]