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EPS8L1 Antibody (PACO00771)

SKU:
PACO00771
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
IF
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€269
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Description

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EPS8L1 Antibody (PACO00771)

The EPS8L1 Polyclonal Antibody (PACO00771) is a valuable tool for researchers studying EPS8L1, a protein involved in various cellular processes such as cell growth and migration. This antibody, generated in rabbits, demonstrates high specificity and sensitivity in detecting EPS8L1 in human samples, making it an ideal choice for Western blot applications. By specifically recognizing the EPS8L1 protein, this antibody enables researchers to analyze its expression and function in different cell types, offering insights into its role in cancer and cell signaling pathways.

EPS8L1 is known to play a crucial role in cell proliferation, cell motility, and cytoskeletal rearrangement, making it a potential target for research in cancer and other diseases involving abnormal cell growth. By studying the function of EPS8L1, researchers can gain a better understanding of its involvement in cellular processes and its potential as a therapeutic target. The EPS8L1 Polyclonal Antibody is a valuable resource for investigating the biological functions of EPS8L1 and its implications in various disease contexts.

Antibody Name:EPS8L1 Antibody
Antibody SKU:PACO00771
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC, IF
Recommended Dilutions:WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000
Species Reactivity:Human, Mouse
Immunogen:synthesized peptide derived from the Internal region of human Eps8L1.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:EPS8L1; DRC3; EPS8R1; PP10566; Epidermal growth factor receptor kinase substrate 8-like protein 1; EPS8-like protein 1; Epidermal growth factor receptor pathway substrate 8-related protein 1; EPS8-related protein 1
UniProt Protein Function:EPS8L1: Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. Belongs to the EPS8 family. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Adaptor/scaffold

Chromosomal Location of Human Ortholog: 19q13.42

Cellular Component: cytoplasm; protein complex

Molecular Function:actin binding; protein binding; Rac guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity; T cell receptor binding

Biological Process: regulation of Rho protein signal transduction; Rho protein signal transduction

NCBI Summary:This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. At least two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:Q8TE68
NCBI GenInfo Identifier:296439363
NCBI Gene ID:54869
NCBI Accession:Q8TE68.3
UniProt Secondary Accession:Q8TE68,Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0
UniProt Related Accession:Q8TE68
Molecular Weight:55,807 Da
NCBI Full Name:Epidermal growth factor receptor kinase substrate 8-like protein 1
NCBI Synonym Full Names:EPS8 like 1
NCBI Official Symbol:EPS8L1  
NCBI Official Synonym Symbols:DRC3; EPS8R1; PP10566  
NCBI Protein Information:epidermal growth factor receptor kinase substrate 8-like protein 1
UniProt Protein Name:Epidermal growth factor receptor kinase substrate 8-like protein 1
UniProt Synonym Protein Names:Epidermal growth factor receptor pathway substrate 8-related protein 1; EPS8-related protein 1
Protein Family:Epidermal growth factor receptor kinase substrate 8-like protein
UniProt Gene Name:EPS8L1  
UniProt Entry Name:ES8L1_HUMAN

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