The EPM2AIP1 Polyclonal Antibody (PAC037046) is a vital tool for researchers studying EPM2AIP1, a protein associated with epilepsy. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting EPM2AIP1 in human samples, making it ideal for immunohistochemistry and immunofluorescence experiments.EPM2AIP1, also known as epilepsy-associated protein with a microtubule-interacting domain-containing protein 1, is linked to the onset and progression of epilepsy, making it a crucial target for investigation in neurological research.
By utilizing the EPM2AIP1 Polyclonal Antibody, researchers can elucidate the role of this protein in epilepsy pathogenesis and potentially identify novel therapeutic strategies for managing this debilitating condition.
Antibody Name:
EPM2AIP1 Antibody (PACO37046)
Antibody SKU:
PACO37046
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human EPM2A-interacting protein 1 protein (251-607AA)
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO37046 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human heart tissue using PACO37046 at dilution of 1:100.
Synonyms:
EPM2A-interacting protein 1 (Laforin-interacting protein), EPM2AIP1, KIAA0766
UniProt Protein Function:
EPM2AIP1: Interacts with EPM2A.Protein type: Endoplasmic reticulumChromosomal Location of Human Ortholog: 3p22.1Cellular Component: cytoplasm; nucleoplasmMolecular Function: DNA binding; protein bindingBiological Process: positive regulation of glycogen biosynthetic process; response to insulin stimulus
UniProt Protein Details:
NCBI Summary:
The EPM2A gene, which encodes laforin, is mutated in an autosomal recessive form of adolescent progressive myoclonus epilepsy. The protein encoded by this gene binds to laforin, but its function is not known. This gene is intronless. [provided by RefSeq, Oct 2008]
