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EPM2A Monoclonal Antibody [P3F3AT] (CPAB0558)

SKU:
CPAB0558
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
P3F3AT
Applications:
WB
ELISA
€149
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Description

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EPM2A Monoclonal Antibody [P3F3AT] (CPAB0558)

The EPM2A Polyclonal Antibody (CPAB0558) is specifically designed for researchers studying EPM2A, a protein associated with Lafora disease, a rare form of progressive myoclonic epilepsy. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the EPM2A protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential tool for studying the role of EPM2A in neurological disorders.EPM2A, also known as laforin, plays a crucial role in glycogen metabolism and the formation of Lafora bodies, abnormal structures found in the brains of individuals with Lafora disease.

Understanding the function of EPM2A is essential for unraveling the molecular mechanisms underlying this debilitating condition and developing targeted treatments. By using the EPM2A Polyclonal Antibody, researchers can gain valuable insights into the pathophysiology of Lafora disease and potentially identify novel therapeutic strategies for patients.

Product Name:EPM2A Antibody
Product Sku:CPAB0558
Size:5μg
Host Species:Mouse
Immunogen:Anti-human EPM2A mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human EPM2A amino acids 243-331 purified from Ecoli.
Clone:P3F3AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:EPM2A antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:EPM2A is a dual-specificity phosphatase which associates with polyribosomes. The EPM2A protein may be involved in the regulation of glycogen metabolism. Mutations in the EPM2A gene have been linked to myoclonic epilepsy of Lafora.
Synonyms:Laforin, Lafora PTPase, LAFPTPase, EPM2A, EPM2, MELF, epilepsy progressive myoclonus type 2A Lafora disease.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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