The EPHX2 Polyclonal Antibody (CAB1885) is a valuable tool for researchers studying the EPHX2 gene, which encodes the enzyme epoxide hydrolase 2. Epoxide hydrolases play a key role in the metabolism and detoxification of xenobiotics and endogenous compounds, making them important in drug metabolism and environmental toxicology studies. This antibody, produced in rabbits, is highly specific for human samples and is suitable for use in Western blot applications.EPHX2 is involved in the hydrolysis of epoxide compounds, converting them into less toxic and more water-soluble substances.
Dysregulation of EPHX2 activity has been linked to various diseases, including cancer, cardiovascular disorders, and neurodegenerative conditions. By targeting EPHX2 with this polyclonal antibody, researchers can gain insights into its expression levels and cellular localization in different tissues, aiding in the understanding of its role in health and disease. Unlock the potential of EPHX2 research with this reliable and sensitive antibody.
Product Name:
EPHX2 Rabbit Polyclonal Antibody
SKU:
CAB1885
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-240 of human EPHX2 (NP_001970.2).
This gene encodes a member of the epoxide hydrolase family. The protein, found in both the cytosol and peroxisomes, binds to specific epoxides and converts them to the corresponding dihydrodiols. Mutations in this gene have been associated with familial hypercholesterolemia. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
2053
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using EPHX2 antibody (CAB1885) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
