The Ephrin B2 Rabbit Monoclonal Antibody is a powerful tool for researchers studying Ephrin B2, a key player in the development and function of the nervous system. This antibody, developed using rabbit monoclonal technology, exhibits high specificity and sensitivity when detecting Ephrin B2 in experimental samples, particularly in Western blot applications. By binding to the Ephrin B2 protein, researchers can confidently analyze its expression in various cell types, paving the way for advancements in neuroscience and neurodevelopmental research.Ephrin B2 is a critical signaling molecule involved in processes such as neuronal migration, axon guidance, and synaptic plasticity, making it an essential target for studies focused on neurological disorders and brain development.
Dysregulation of Ephrin B2 has been implicated in conditions like Alzheimer's disease, schizophrenia, and epilepsy, highlighting its importance in understanding the pathophysiology of these disorders. By unraveling the mechanisms underlying Ephrin B2 function, researchers can potentially uncover new therapeutic targets for treating neurological conditions and improving cognitive function.
Product Name:
Ephrin B2 Rabbit Monoclonal Antibody
SKU:
CAB11349
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human EFNB2 (P52799).
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors.
Purification Method:
Affinity purification
Gene ID:
1948
Clone Number:
ARC0576
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Ephrin B2 Rabbit mAb (CAB11349) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
