The Ephrin-A3 Polyclonal Antibody (CAB2724) is a valuable tool for researchers studying the ephrin-A3 protein, a critical player in cell signaling pathways involved in development, tissue regeneration, and disease progression. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.Ephrin-A3 is a member of the ephrin family of proteins, which binds to Eph receptors to regulate cell migration, adhesion, and axon guidance. Dysregulation of ephrin-A3 signaling has been implicated in various diseases, including cancer, neurological disorders, and cardiovascular diseases.
By targeting ephrin-A3 with this antibody, researchers can analyze its expression levels and localization in different cell types, providing valuable insights into its role in these pathologies.The Ephrin-A3 Polyclonal Antibody is a powerful tool for elucidating the complex functions of ephrin-A3 and its involvement in disease processes. Its high specificity and sensitivity make it a reliable choice for immunology and cancer research studies aiming to uncover the mechanisms underlying disease progression and identify potential therapeutic targets.
Product Name:
EFNA3 Rabbit Polyclonal Antibody
SKU:
CAB2724
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 23-214 of human EFNA3 (NP_004943.1).
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin.
Purification Method:
Affinity purification
Gene ID:
1944
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using EFNA3 antibody (CAB2724) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.
