The Ephrin-A1 Polyclonal Antibody (CAB5341) is a crucial tool for researchers studying ephrin-A1, a member of the ephrin family of cell surface molecules known for their role in cell signaling and development. This antibody, raised in rabbits, is highly specific to human samples and is validated for use in various research applications including Western blotting. By binding to ephrin-A1, this antibody allows for detection and analysis of the protein in different cell types, making it invaluable for studies in developmental biology and cancer research.Ephrin-A1 is known to play a significant role in various cellular processes such as cell migration, adhesion, and axon guidance.
Its dysregulation has been linked to developmental disorders and cancer progression, making it a promising target for therapeutic interventions. Understanding the function and expression of ephrin-A1 is essential for uncovering its potential as a biomarker or target for drug development in various diseases.Overall, the Ephrin-A1 Polyclonal Antibody (CAB5341) serves as a vital tool for researchers seeking to unravel the complexities of ephrin-A1 biology and its implications in health and disease. Its high specificity and reliability make it an ideal choice for studies aiming to dissect the molecular mechanisms underlying ephrin-A1 function.
Product Name:
EFNA1 Rabbit Polyclonal Antibody
SKU:
CAB5341
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 19-182 of human EFNA1 (NP_004419.2).
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis.
Purification Method:
Affinity purification
Gene ID:
1942
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using EFNA1 Rabbit pAb (CAB5341) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
