The EphB6 Polyclonal Antibody (CAB14728) is a valuable tool for researchers studying EphB6, a member of the Eph receptor tyrosine kinase family that plays a crucial role in cell signaling and tissue development. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the EphB6 protein, this antibody enables researchers to detect and analyze EphB6 expression in various cell types, making it an ideal choice for studies in developmental biology, cancer research, and neuroscience.
EphB6 is known to be involved in cell migration, adhesion, and axon guidance, making it an important target for research aimed at understanding cell behavior and tissue formation. Dysregulation of EphB6 signaling has been implicated in various diseases, including cancer, neurological disorders, and cardiovascular conditions. By studying EphB6 expression and function using this polyclonal antibody, researchers can gain valuable insights into the molecular mechanisms underlying these diseases and potentially identify new therapeutic opportunities.
Product Name:
EPHB6 Rabbit Polyclonal Antibody
SKU:
CAB14728
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 615-729 of human EPHB6 (NP_001267724.2).
Membrane, Secreted, Single-pass type I membrane protein.
Calculated MW:
111kDa
Observed MW:
111kDa
This gene encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins. Unlike other members of this family, the encoded protein does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor progression, suggesting that the protein may suppress tumor invasion and metastasis. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
2051
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EPHB6 Rabbit pAb (CAB14728) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
