EPHB4 Rabbit Polyclonal Antibody (CAB3293)
- SKU:
- CAB3293
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cardiovascular
Description
Product Name: | EPHB4 Rabbit Polyclonal Antibody |
SKU: | CAB3293 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-540 of human EPHB4 (NP_004435.3). |
Sequence: | AVCQ CRVG YFRA RTDP RGAP CTTP PSAP RSVV SRLN GSSL HLEW SAPL ESGG REDL TYAL RCRE CRPG GSCA PCGG DLTF DPGP RDLV EPWV VVRG LRPD FTYT FEVT ALNG VSSL ATGP VPFE PVNV TTDR EVPP AVSD IRVT RSSP SSLS LAWA VPRA PSGA VLDY EVKY HEKG AEGP SSVR FLKT SENR AELR GLKR GASY LVQV RARS EAGY GPFG QEHH SQTQ LDES EGWR EQLA L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | HTK; MYK1; HFASD; CMAVM2; LMPHM7; TYRO11; EPHB4 |
Positive Sample: | Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Single-pass type I membrane protein. |
Calculated MW: | 108kDa |
Observed MW: | 108kDa |
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.
Purification Method: | Affinity purification |
Gene ID: | 2050 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |