EPHB2 Rabbit Polyclonal Antibody (CAB9813)
- SKU:
- CAB9813
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Neuroscience
Description
Product Name: | EPHB2 Rabbit Polyclonal Antibody |
SKU: | CAB9813 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 250-540 of human EPHB2 (NP_059145.2). |
Sequence: | PIGR CMCK AGFE AVEN GTVC RGCP SGTF KANQ GDEA CTHC PINS RTTS EGAT NCVC RNGY YRAD LDPL DMPC TTIP SAPQ AVIS SVNE TSLM LEWT PPRD SGGR EDLV YNII CKSC GSGR GACT RCGD NVQY APRQ LGLT EPRI YISD LLAH TQYT FEIQ AVNG VTDQ SPFS PQFA SVNI TTNQ AAPS AVSI MHQV SRTV DSIT LSWS QPDQ PNGV ILDY ELQY YEKE LSEY NATA IKSP TNTV TVQG LKAG AIYV FQVR ARTV AGYG RYSG KMYF QTMT EAEY QTSI QEK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | DRT; EK5; ERK; CAPB; Hek5; PCBC; EPHT3; Tyro5; BDPLT22; EPHB2 |
Positive Sample: | NCI-H460,HepG2,HeLa,HT-1080,SW620,Mouse brain,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cell projection, Single-pass type I membrane protein, axon, dendrite. |
Calculated MW: | 117kDa |
Observed MW: | 117kDa |
This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 2048 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |