The EPHA5 Polyclonal Antibody (CAB14238) is a vital tool for researchers studying the EPHA5 protein, a member of the ephrin receptor subfamily of protein-tyrosine kinases. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been rigorously validated for use in Western blot applications.EPHA5 is known to play a key role in various biological processes, including cell adhesion, migration, and axon guidance. Dysregulation of EPHA5 has been implicated in neurological disorders, cancer, and other diseases, making it an attractive target for further research.
By utilizing the EPHA5 Polyclonal Antibody, researchers can detect and analyze the expression levels of EPHA5 in different cell types, aiding in the investigation of its function and potential therapeutic applications.Overall, the EPHA5 Polyclonal Antibody is a valuable tool for researchers in the fields of neuroscience, oncology, and developmental biology, offering insights into the role of EPHA5 in health and disease.
Product Name:
EPHA5 Rabbit Polyclonal Antibody
SKU:
CAB14238
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human EPHA5 (NP_004430.4).
Cell membrane, Cell projection, Single-pass type I membrane protein, axon, dendrite.
Calculated MW:
115kDa
Observed MW:
115kDa
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Alternatively spliced transcript variants encoding different isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
2044
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EPHA5 Rabbit pAb (CAB14238) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
