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EPHA2 Monoclonal Antibody [P3D7AT] (CPAB0557)

SKU:
CPAB0557
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2b
Clone:
P3D7AT
Applications:
WB
ELISA
IHC
€149
Frequently bought together:

Description

system_update_alt Datasheet

EPHA2 Monoclonal Antibody [P3D7AT] (CPAB0557)

The EphA2 Polyclonal Antibody (CPAB0557) is a valuable tool for researchers studying EphA2, a receptor tyrosine kinase that plays a key role in cell signaling and regulation. This antibody is raised in rabbits and has been shown to have high reactivity with human samples, making it suitable for use in a variety of research applications, including Western blot analysis.EphA2 is known to be involved in a wide range of biological processes, including cell adhesion, migration, and survival. Dysregulation of EphA2 signaling has been implicated in various diseases, such as cancer, where it promotes tumor growth and metastasis.

By using the EphA2 Polyclonal Antibody, researchers can study the expression and activity of EphA2 in different cell types and gain insights into its role in disease development and progression.Overall, the EphA2 Polyclonal Antibody is a valuable tool for scientists interested in investigating the functions of EphA2 and its potential as a therapeutic target in diseases like cancer. Its specificity and reliability make it an essential component of any research study aiming to elucidate the complex signaling pathways involving EphA2.

Product Name:EPHA2 Antibody
Product Sku:CPAB0557
Size:5μg
Host Species:Mouse
Immunogen:Anti-human EPHA2 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human EPHA2 amino acids 1-154 purified from Ecoli.
Clone:P3D7AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA, Immunohistochemistry
Purification Method:EPHA2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:EPHA2 is a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors are implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The EPHA2 gene encodes a protein that binds ephrin-A ligands. Mutations in the EPHA2 gene are the origin of certain genetically-related cataract disorders.
Synonyms:EPH receptor A2, Ephrin type-A receptor 2, Tyrosine-protein kinase receptor ECK, Epithelial cell kinase, EPHA2, ECK, ARCC2.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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