EPHA10 Antibody (PACO16262)
- SKU:
- PACO16262
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
EPHA10 Antibody (PACO16262)
The EPHA10 Polyclonal Antibody (PAC016262) is a valuable tool for researchers studying EPHA10, a member of the EPH receptor family involved in various cellular processes such as cell adhesion, migration, and differentiation. This antibody, generated in rabbits, displays high specificity and reactivity towards human samples, making it suitable for applications such as Western blotting.EPHA10 is known to play a role in signaling pathways that regulate cell growth, survival, and development, making it a promising target for studies in cancer biology and developmental biology. By binding specifically to the EPHA10 protein, this antibody enables precise detection and analysis of EPHA10 expression levels in different cell types, providing valuable insights into its function and potential therapeutic implications.
The EPHA10 Polyclonal Antibody is a valuable tool for researchers seeking to further understand the molecular mechanisms underlying EPHA10 function and its potential involvement in various disease processes. Its high specificity and sensitivity make it an essential component in immunology and cancer research studies aimed at targeting EPHA10 for therapeutic interventions.
| Antibody Name: | EPHA10 Antibody (PACO16262) |
| Antibody SKU: | PACO16262 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human EPHA10 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16262(EPHA10 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using PACO16262(EPHA10 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | Ephrin receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility in neuronal and epithelial cells |
| Synonyms: | EPH receptor A10 |
| UniProt Protein Function: | EphA10: Receptor for members of the ephrin-A family. Binds to EFNA3, EFNA4 and EFNA5. Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Kinase, protein; Protein kinase, tyrosine (receptor); Membrane protein, integral; Protein kinase, TK; EC 2.7.10.1; TK group; Eph family Chromosomal Location of Human Ortholog: 1p34.3 Cellular Component: plasma membrane Molecular Function:protein binding Biological Process: ephrin receptor signaling pathway |
| NCBI Summary: | Ephrin receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility in neuronal and epithelial cells (Aasheim et al., 2005 [PubMed 15777695]). See MIM 179610 for additional background on Eph receptors and ephrins.[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q5JZY3 |
| NCBI GenInfo Identifier: | 476007830 |
| NCBI Gene ID: | 284656 |
| NCBI Accession: | Q5JZY3.2 |
| UniProt Secondary Accession: | Q5JZY3,Q6NW42, A4FU89, J3KPB5, |
| UniProt Related Accession: | Q5JZY3 |
| Molecular Weight: | 97,293 Da |
| NCBI Full Name: | Ephrin type-A receptor 10 |
| NCBI Synonym Full Names: | EPH receptor A10 |
| NCBI Official Symbol: | EPHA10Â Â |
| NCBI Protein Information: | ephrin type-A receptor 10 |
| UniProt Protein Name: | Ephrin type-A receptor 10 |
| Protein Family: | Ephrin type-A receptor |
| UniProt Gene Name: | EPHA10Â Â |
| UniProt Entry Name: | EPHAA_HUMAN |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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