EPHA10 Antibody (PACO03938)
- SKU:
- PACO03938
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
EPHA10 Antibody (PACO03938)
The EphA10 Monoclonal Antibody (PAC00398) is a cutting-edge tool for researchers studying EphA10, a member of the Eph receptor family involved in cell signaling and regulation. This antibody, produced using innovative technology, specifically targets EphA10 and is highly reactive with human samples. Validated for use in various applications, including immunofluorescence and flow cytometry, it provides researchers with a reliable tool for detecting and analyzing EphA10 expression in different cell types.EphA10, a transmembrane protein, plays a crucial role in various biological processes, including cell adhesion, migration, and tissue development.
Its dysregulation has been associated with cancer progression, making it a potential target for cancer therapy research. By studying EphA10 expression and function, researchers can gain insights into its role in cancer development and potentially develop targeted therapies to inhibit its activity in cancer cells.Overall, the EphA10 Monoclonal Antibody offers researchers a valuable tool for investigating the function of EphA10 in health and disease. Its high specificity and sensitivity make it an essential asset for studies in cell biology, cancer research, and drug development.
| Antibody Name: | EPHA10 Antibody |
| Antibody SKU: | PACO03938 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | synthesized peptide derived from the Internal region of human EphA10. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | EPHA10; Ephrin type-A receptor 10 |
| UniProt Protein Function: | EphA10: Receptor for members of the ephrin-A family. Binds to EFNA3, EFNA4 and EFNA5. Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Kinase, protein; Protein kinase, tyrosine (receptor); Membrane protein, integral; Protein kinase, TK; EC 2.7.10.1; TK group; Eph family Chromosomal Location of Human Ortholog: 1p34.3 Cellular Component: plasma membrane Molecular Function:protein binding Biological Process: ephrin receptor signaling pathway |
| NCBI Summary: | Ephrin receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility in neuronal and epithelial cells (Aasheim et al., 2005 [PubMed 15777695]). See MIM 179610 for additional background on Eph receptors and ephrins.[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q5JZY3 |
| NCBI GenInfo Identifier: | 476007830 |
| NCBI Gene ID: | 284656 |
| NCBI Accession: | Q5JZY3.2 |
| UniProt Secondary Accession: | Q5JZY3,Q6NW42, A4FU89, J3KPB5, |
| UniProt Related Accession: | Q5JZY3 |
| Molecular Weight: | 97,293 Da |
| NCBI Full Name: | Ephrin type-A receptor 10 |
| NCBI Synonym Full Names: | EPH receptor A10 |
| NCBI Official Symbol: | EPHA10Â Â |
| NCBI Protein Information: | ephrin type-A receptor 10 |
| UniProt Protein Name: | Ephrin type-A receptor 10 |
| Protein Family: | Ephrin type-A receptor |
| UniProt Gene Name: | EPHA10Â Â |
| UniProt Entry Name: | EPHAA_HUMAN |
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