EPDR1 Antibody (PACO16260)
- SKU:
- PACO16260
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
EPDR1 Antibody (PACO16260)
The EPDR1 Polyclonal Antibody (PAC016260) is a valuable tool for researchers studying the EPDR1 protein, a key player in various cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been extensively validated for use in Western blot applications. By specifically binding to the EPDR1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for research in molecular biology and cell signaling pathways.
EPDR1, also known as an essential protein for desert locust reproduction, is involved in critical functions such as cell growth, differentiation, and survival. Its role in regulating these processes highlights its importance in development and disease progression. By gaining insights into the functions of EPDR1, researchers can expand their understanding of cellular mechanisms and potentially uncover new therapeutic targets for a wide range of disorders, from cancer to neurodegenerative diseases.
| Antibody Name: | EPDR1 Antibody (PACO16260) |
| Antibody SKU: | PACO16260 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Fusion protein of human EPDR1 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO16260(EPDR1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
 | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Mouse brain tissue, human fetal muscle tissue, Primary antibody: PACO16260(EPDR1 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO16260(EPDR1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | The protein encoded by this gene is a type II transmembrane protein that is similar to two families of cell adhesion molecules, the protocadherins and ependymins. This protein may play a role in calcium-dependent cell adhesion. This protein is glycosylated, and the orthologous mouse protein is localized to the lysosome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. |
| Synonyms: | ependymin related 1 |
| UniProt Protein Function: | EPDR1: is a type II transmembrane protein that is similar to two families of cell adhesion molecules, the protocadherins and ependymins. This protein may play a role in calcium-dependent cell adhesion. This protein is glycosylated, and the orthologous mouse protein is localized to the lysosome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. [provided by RefSeq, Aug 2011]Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 7p14.1 |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a type II transmembrane protein that is similar to two families of cell adhesion molecules, the protocadherins and ependymins. This protein may play a role in calcium-dependent cell adhesion. This protein is glycosylated, and the orthologous mouse protein is localized to the lysosome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. [provided by RefSeq, Aug 2011] |
| UniProt Code: | Q9UM22 |
| NCBI GenInfo Identifier: | 13124620 |
| NCBI Gene ID: | 54749 |
| NCBI Accession: | Q9UM22.2 |
| UniProt Secondary Accession: | Q9UM22,Q06BL0, Q99M77, A8K4C0, C9JYS3 |
| UniProt Related Accession: | Q9UM22 |
| Molecular Weight: | 18,672 Da |
| NCBI Full Name: | Mammalian ependymin-related protein 1 |
| NCBI Synonym Full Names: | ependymin related 1 |
| NCBI Official Symbol: | EPDR1Â Â |
| NCBI Official Synonym Symbols: | EPDR; UCC1; MERP1; MERP-1Â Â |
| NCBI Protein Information: | mammalian ependymin-related protein 1 |
| UniProt Protein Name: | Mammalian ependymin-related protein 1 |
| UniProt Synonym Protein Names: | Upregulated in colorectal cancer gene 1 protein |
| Protein Family: | Mammalian ependymin-related protein |
| UniProt Gene Name: | EPDR1Â Â |
| UniProt Entry Name: | EPDR1_HUMAN |
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