The EpCAM Rabbit Monoclonal Antibody is a valuable tool for researchers studying EpCAM, a cell surface glycoprotein involved in cell adhesion and signaling. This antibody, generated in rabbits, offers high specificity and sensitivity for detecting EpCAM in human samples, making it ideal for use in applications such as immunohistochemistry and flow cytometry.EpCAM, also known as CD326, is a biomarker associated with various cancers, including breast, colon, and lung cancer. Its overexpression has been linked to tumor progression and metastasis, making it a promising target for cancer therapy and diagnosis.
By using the EpCAM Rabbit Monoclonal Antibody, researchers can accurately analyze EpCAM expression levels in tumor tissues and study its role in cancer development and progression.Overall, the EpCAM Rabbit Monoclonal Antibody is a valuable tool for researchers interested in studying EpCAM and its implications in cancer biology. Its high specificity and sensitivity make it a reliable choice for various research applications, providing critical insights into the role of EpCAM in cancer pathogenesis.
Product Name:
EpCAM Rabbit Monoclonal Antibody
SKU:
CAB1107
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human EpCAM (P16422).
Cell junction, Lateral cell membrane, Single-pass type I membrane protein, tight junction.
Calculated MW:
35kDa
Observed MW:
40kDa
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.
Purification Method:
Affinity purification
Gene ID:
4072
Clone Number:
ARC0521
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using EpCAM Rabbit mAb (CAB1107) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.
