The EPC1 Polyclonal Antibody (CAB5807) is a valuable tool for researchers studying EPC1, a key component of the NuA4 histone acetyltransferase complex involved in gene regulation and chromatin remodeling. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically detecting the EPC1 protein, researchers can gain insights into its functions and interactions in various cellular processes.
EPC1 is essential for the regulation of gene expression and chromatin structure, making it a crucial player in multiple cellular pathways. Its involvement in epigenetic mechanisms and transcriptional regulation suggests its potential implications in cancer, developmental disorders, and other diseases. Investigating the role of EPC1 with this antibody can provide valuable information for understanding its impact on cellular function and disease progression.
Product Name:
EPC1 Rabbit Polyclonal Antibody
SKU:
CAB5807
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human EPC1 (NP_079485.1).
This gene encodes a member of the polycomb group (PcG) family. The encoded protein is a component of the NuA4 histone acetyltransferase complex and can act as both a transcriptional activator and repressor. The encoded protein has been linked to apoptosis, DNA repair, skeletal muscle differentiation, gene silencing, and adult T-cell leukemia/lymphoma. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
80314
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using EPC1 antibody (CAB5807) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
