The ePAC1 Rabbit Monoclonal Antibody (CAB4149) is a highly specific and sensitive tool for researching ePAC1, a protein involved in cellular signaling pathways related to cyclic AMP (cAMP) and PKA activation. This antibody, generated in rabbits, has been validated for use in techniques like Western blotting, immunohistochemistry, and immunofluorescence, allowing for accurate detection and analysis of ePAC1 expression in various cell types.ePAC1, also known as exchange protein directly activated by cAMP 1, plays a crucial role in regulating intracellular cAMP levels and downstream signaling cascades that impact processes like cell growth, differentiation, and metabolism.
Its involvement in various physiological and pathological conditions, including neurological disorders and cardiovascular diseases, makes it a promising target for further investigation and potential therapeutic interventions.By utilizing the ePAC1 Rabbit Monoclonal Antibody (CAB4149) in research studies, scientists can gain valuable insights into the molecular mechanisms underlying cAMP/PKA signaling and its implications for disease progression and treatment strategies. This antibody offers a reliable tool for elucidating the function of ePAC1 in diverse biological contexts, paving the way for new discoveries in cell biology, pharmacology, and medical research.
Product Name:
Epac1/RAPGEF3 Rabbit Monoclonal Antibody
SKU:
CAB4149
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 824-923 of human Epac1/RAPGEF3 (O95398).
Enables guanyl-nucleotide exchange factor activity and protein domain specific binding activity. Involved in several processes, including positive regulation of protein modification process
Purification Method:
Affinity purification
Gene ID:
10411
Clone Number:
ARC0908
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Epac1/RAPGEF3 Rabbit mAb (CAB4149) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
