The EP400 Polyclonal Antibody (CAB12151) is a valuable tool for researchers studying the EP400 protein, a key regulator of gene expression and DNA repair processes. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the EP400 protein, researchers can detect and analyze its presence in various cell types, making it an essential reagent for investigations in molecular biology and cancer research.EP400 is a crucial factor in chromatin remodeling and transcriptional regulation, playing a role in diverse cellular processes such as DNA replication and repair, cell cycle progression, and cell differentiation.
Dysregulation of the EP400 protein has been linked to various diseases, including cancer and developmental disorders, making it an attractive target for therapeutic intervention. Research into the functions and mechanisms of EP400 holds promise for the development of novel treatments for these conditions.
Product Name:
EP400 Rabbit Polyclonal Antibody
SKU:
CAB12151
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 90-330 of human EP400 (NP_056224.3).
Predicted to enable several functions, including ATP binding activity; ATP-dependent chromatin remodeler activity; and protein antigen binding activity. Involved in histone H2A acetylation and histone H4 acetylation. Part of NuA4 histone acetyltransferase complex and Swr1 complex.
Purification Method:
Affinity purification
Gene ID:
57634
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EP400 Rabbit pAb (CAB12151) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
