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EOMES Polyclonal Antibody (CAB18222)

SKU:
CAB18222
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
€129 - €359
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:EOMES Polyclonal Antibody
SKU:CAB18222
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 463-686 of human EOMES (NP_005433.2).
Sequence:QIVP GGRY GVQS FFPE PFVN TLPQ ARYY NGER TVPQ TNGL LSPQ QSEE VANP PQRW LVTP VQQP GTNK LDIS SYES EYTS STLL PYGI KSLP LQTS HALG YYPD PTFP AMAG WGGR GSYQ RKMA AGLP WTSR TSPT VFSE DQLS KEKV KEEI GSSW IETP PSIK SLDS NDSG VYTS ACKR RRLS PSNS SNEN SPSI KCED INAE EYSK DTSK GMGG YYAF YTTP
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:TBR2; EOMES
Positive Sample:Rat brain
Cellular Localization:nucleus
Calculated MW:73kDa
Observed MW:70kDa

This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:8320
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of Rat brain, using EOMES antibody (CAB18222) at 1:700 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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