The ENTPD8 Polyclonal Antibody (PACO09105) is a valuable tool for researchers studying ENTPD8, a member of the ectonucleoside triphosphate diphosphohydrolase (ENTPD) family that plays a role in the metabolism of nucleotides and purines. This antibody is produced in rabbits and exhibits high reactivity with human samples, making it a reliable choice for Western blot applications.ENTPD8 is involved in regulating extracellular nucleotide levels, which are important in various physiological processes such as inflammation, immunity, and cell proliferation.
Dysregulation of ENTPD8 has been linked to autoimmune diseases, cancer, and neurological disorders, making it a promising target for therapeutic interventions.By utilizing the ENTPD8 Polyclonal Antibody, researchers can detect and analyze ENTPD8 protein expression in different cell types, allowing for deeper insights into its function and potential implications in disease pathology. This antibody is a valuable tool for investigations in immunology, cancer biology, and other fields where nucleotide metabolism is a key factor.
ENTPD8: Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolysis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. Has activity toward ATP, ADP, UTP and UDP, but not toward AMP. Belongs to the GDA1/CD39 NTPase family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Nucleotide Metabolism - pyrimidine; Nucleotide Metabolism - purine; Membrane protein, multi-pass; Hydrolase; Membrane protein, integral; EC 3.6.1.5Chromosomal Location of Human Ortholog: 9q34.3
