The ENTPD6 Polyclonal Antibody (CAB15655) is a valuable tool for researchers studying ENTPD6, an enzyme involved in purinergic signaling and nucleotide metabolism. This antibody, produced in rabbits, shows high specificity and sensitivity towards human samples, making it suitable for Western blot applications. By binding to the ENTPD6 protein, this antibody allows for the detection and analysis of ENTPD6 expression in various cell types, making it ideal for studies in cell biology, metabolism, and signal transduction pathways.ENTPD6, also known as NTPDase 6, plays a crucial role in regulating extracellular nucleotide levels and modulating purinergic signaling cascades.
Dysregulation of ENTPD6 has been implicated in various diseases, including cancer, inflammation, and neurological disorders. Therefore, investigating the function and expression of ENTPD6 is essential for understanding its role in these pathological conditions and developing targeted therapies.Overall, the ENTPD6 Polyclonal Antibody (CAB15655) offers researchers a reliable tool for studying ENTPD6 protein expression and function, providing insights into its biological roles and potential therapeutic applications in disease.
Product Name:
ENTPD6 Rabbit Polyclonal Antibody
SKU:
CAB15655
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 61-300 of human ENTPD6 (NP_001304870.1).
Golgi apparatus membrane, Secreted, Single-pass type II membrane protein.
Calculated MW:
53kDa
Observed MW:
45kDa
ENTPD6 is similar to E-type nucleotidases (NTPases). NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD6 contains 4 apyrase-conserved regions which are characteristic of NTPases. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
955
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ENTPD6 Rabbit pAb (CAB15655) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
