The ENTPD5 Polyclonal Antibody (CAB8108) is a research tool specifically designed for studying ENTPD5, a crucial enzyme involved in nucleotide metabolism and cellular signaling pathways. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the ENTPD5 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential tool for researchers in the fields of biochemistry and cell biology.ENTPD5, also known as ectonucleoside triphosphate diphosphohydrolase 5, plays a key role in regulating the levels of extracellular nucleotides and modulating purinergic signaling, which is essential for various physiological processes such as inflammation, immune response, and cell proliferation.
Dysregulation of ENTPD5 has been implicated in diseases like cancer, neurodegenerative disorders, and cardiovascular diseases, making it a promising target for therapeutic interventions. Understanding the functions of ENTPD5 can provide valuable insights into the development of new treatments for these conditions.
Product Name:
ENTPD5 Rabbit Polyclonal Antibody
SKU:
CAB8108
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 149-428 of human ENTPD5 (NP_001240.1).
The protein encoded by this gene is similar to E-type nucleotidases (NTPases)/ecto-ATPase/apyrases. NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD5 contains 4 apyrase-conserved regions which is characteristic of NTPases.
Purification Method:
Affinity purification
Gene ID:
957
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of U2OS cells using ENTPD5 antibody (CAB8108) at dilution of 1:100. Blue: DAPI for nuclear staining.
