The ENPP7 Polyclonal Antibody (CAB2912) is a valuable tool for researchers studying the ENPP7 enzyme, which plays a key role in lipid metabolism and inflammation regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the ENPP7 protein, researchers can accurately detect and analyze its expression in various cell types.ENPP7, also known as Autotaxin-2, is involved in the conversion of lysophospholipids into bioactive lysophosphatidic acid (LPA), which is a potent signaling molecule implicated in various physiological and pathological processes such as cancer progression, inflammation, and fibrosis.
The ENPP7 Polyclonal Antibody serves as a critical tool for investigating the role of ENPP7 in these processes and for developing targeted therapies aimed at modulating lipid signaling pathways.With its specificity and reliability, the ENPP7 Polyclonal Antibody is an essential asset for researchers in the fields of lipid biology, inflammation, and cancer research, enabling a better understanding of ENPP7 function and its potential as a therapeutic target.
Product Name:
ENPP7 Rabbit Polyclonal Antibody
SKU:
CAB2912
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human ENPP7 (Q6UWV6).
The protein encoded by this gene is an intestinal alkaline sphingomyelin phosphodiesterase that converts sphingomyelin to ceramide and phosphocholine. The encoded protein is anchored in the cell membrane, and it may function to protect the intestinal mucosa from inflammation and tumorigenesis. This protein is glycosylated and also exhibits lysophosphatidylcholine hydrolase activity.
Purification Method:
Affinity purification
Gene ID:
339221
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of HepG2 cells, using ENPP7 antibody (CAB2912) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
