The FITC Anti-Human CD203c Antibody (NP4D6) offered by Assay Genie is a valuable tool for researchers studying CD203c, a cell surface molecule associated with immune responses and inflammation regulation. This antibody, designed for use with human samples, is conjugated with FITC for easy detection and visualization in flow cytometry and immunofluorescence applications. Its specificity for CD203c makes it perfect for investigating the role of this protein in allergic reactions, inflammatory conditions, and other immune-related processes.CD203c, also known as ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3), participates in the purinergic signaling pathway and has been implicated in various physiological and pathological processes.
By targeting CD203c with this antibody, researchers can delve into its function in immune cells, endothelial cells, and tumor microenvironments. Understanding the expression and localization of CD203c can provide insights into disease mechanisms and potential therapeutic targets in cancer, autoimmune diseases, and vascular disorders.With its specificity, sensitivity, and versatility, the FITC Anti-Human CD203c Antibody (NP4D6) from Assay Genie is a valuable addition to any research investigating the role of CD203c in health and disease.
Product Title:
FITC Anti-Human CD203c Antibody [NP4D6]
SKU:
AGEL3399
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
NP4D6
Synonyms:
E-NPP3; ENPP3;PD-Ibeta;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
O14638
Gene ID:
5169Â
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD203c, a transmembrane protein and a member of the ectoenzyme family, is involved in the hydrolysis of extracellular oligonucleotides, nucleoside phosphates, and NAD (possesses ATPase and ATP pyrophosphatase activity). The molecular weight of CD203c is between 130 and 150 kD under reducing conditions and 270 kD under non-reducing conditions. CD203c is expressed on basophils and mast cells, and is highly expressed on activated basophils. Secretory glands in endometrium and glioma cells are also positive. CD203c is a multifunctional ectoenzyme involved in the clearance of extracellular nucleotides whose substrates include nucleoside triphosphates, nucleoside diphosphates, cAMP, and NAD.