ENPP2 Rabbit Polyclonal Antibody (CAB2522)
- SKU:
- CAB2522
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ENPP2 Rabbit Polyclonal Antibody |
SKU: | CAB2522 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 564-863 of human ENPP2 (NP_001035181.1). |
Sequence: | DLGC TCDD KVEP KNKL DELN KRLH TKGS TEER HLLY GRPA VLYR TRYD ILYH TDFE SGYS EIFL MPLW TSYT VSKQ AEVS SVPD HLTS CVRP DVRV SPSF SQNC LAYK NDKQ MSYG FLFP PYLS SSPE AKYD AFLV TNMV PMYP AFKR VWNY FQRV LVKK YASE RNGV NVIS GPIF DYDY DGLH DTED KIKQ YVEG SSIP VPTH YYSI ITSC LDFT QPAD KCDG PLSV SSFI LPHR PDNE ESCN SSED ESKW VEEL MKMH TARV RDIE HLTS LDFF RKTS RSYP EILT LKTY LHTY ESEI |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ATX; NPP2; ATX-X; PDNP2; LysoPLD; AUTOTAXIN; PD-IALPHA; ENPP2 |
Positive Sample: | HepG2,A-549,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 99kDa |
Observed MW: | 110-115kDa |
The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method: | Affinity purification |
Gene ID: | 5168 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |