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ENO2 Monoclonal Antibody [PAT17D10A] (CPAB0181)

SKU:
CPAB0181
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT17D10A
Applications:
WB
ELISA
€149
Frequently bought together:

Description

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ENO2 Monoclonal Antibody [PAT17D10A] (CPAB0181)

The ENO2 Polyclonal Antibody (CPAB0181) is a valuable tool for researchers studying ENO2, a key enzyme involved in glycolysis and neuronal development. Raised in rabbits, this antibody is highly specific to human ENO2 samples and has been validated for use in Western blot applications. By targeting the ENO2 protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential resource for studies in neurology, metabolism, and cancer research.ENO2, also known as neuron-specific enolase, is essential for energy production in neuronal cells and has been implicated in various neurological disorders and tumors.

Its role in tumor growth and metastasis has sparked interest in targeting ENO2 for therapeutic interventions in cancer treatment. Understanding the function of ENO2 is crucial for uncovering new treatment strategies and diagnostic tools for diseases associated with altered glycolytic metabolism.Overall, the ENO2 Polyclonal Antibody (CPAB0181) provides researchers with a reliable tool for studying the expression and function of ENO2 in various biological contexts, advancing our understanding of its role in health and disease.

Product Name:ENO2 Antibody
Product Sku:CPAB0181
Size:5μg
Host Species:Mouse
Immunogen:Anti-human ENO2 mAb, clone PAT17D1A, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ENO2 protein 1-434 amino acids  purified from Ecoli.
Clone:PAT17D10A
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:ENO2 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b
Background:Neuron-specificenolase also caled NSE is a glycolytic isoenzyme which is situated in central and peripheral neurons and neuroendocrine cells. Enolase-2 is released into the CSF when neural tissue is injured. Neoplasms derived from neural or neuroendocrine tissue release Enolase-2 into the blood. Enolase-2 is a useful substance that has been detected in patients with certain tumors, such as neuroblastoma, small cell lung cancer, medullary thyroid cancer, carcinoid tumors, pancreatic endocrine tumors, and melanoma. ENO2 is 1 of the 3 enolase isoenzymes found in mammals. ENO2 isoenzyme, is found in mature neurons and cells of neuronal origin. An exchange from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates.
Synonyms:Gamma-enolase, EC 4.2.1.11, 2-phospho-D-glycerate hydro-lyase, Neural enolase, Neuron-specific enolase, NSE, Enolase 2, ENO2.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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