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ENO1 Monoclonal Antibody [PAT1G7AT] (CPAB0242)

SKU:
CPAB0242
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PAT1G7AT
Applications:
WB
ELISA
FC
€149
Frequently bought together:

Description

system_update_alt Datasheet

ENO1 Monoclonal Antibody [PAT1G7AT] (CPAB0242)

The ENO1 Polyclonal Antibody (CPAB0242) is a vital tool for research involving ENO1, a key enzyme involved in glycolysis and various cellular processes. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in a variety of applications, including Western blot and immunohistochemistry.ENO1, also known as alpha-enolase, plays a crucial role in energy metabolism and cellular growth, making it a significant target in cancer research and other fields. The ENO1 Polyclonal Antibody facilitates the detection and analysis of ENO1 protein in various cell types, offering researchers valuable insights into its function and potential therapeutic applications.

Studies have shown that dysregulation of ENO1 is associated with tumorigenesis, making it a promising candidate for targeted therapies in cancer treatment. By understanding the role of ENO1 in disease development and progression, researchers can make strides in developing new treatment strategies and improving patient outcomes.

Product Name:ENO1 Antibody
Product Sku:CPAB0242
Size:5μg
Host Species:Mouse
Immunogen:Anti-human ENO1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human ENO1 amino acids 1-434 purified from Ecoli.
Clone:PAT1G7AT.
Reactivity:Human
Applications:Western Blot, ELISA, Flow Cytometry
Purification Method:ENO1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2a
Background:ENO1 is a homodimeric soluble protein that encodes a smaller monomeric structural lens protein, tau-crystallin. ENO1 is a glycolytic enzyme expressed in mainly all tissues. ENO1 isoenzyme full length protein is found in the cytoplasm. The shorter protein is formed from another translation start that is restricted to the nucleus, and binds to a component in the c-myc promoter. ENO1 is involved in anaerobic metabolism under hypoxic conditions and plays a role as a cell surface plasminogen receptor during tissue invasion. Irregular expression of Enolase-1 is linked with tumor progression in several cases of breast and lung cancer. Enolase-1 is as an auto antigen associated with Hashimoto's encephalopathy and severe asthma. ENO1 is the target protein of serum anti-endothelial antibody in Behcet's disease.
Synonyms:NNE, PPH, MPB1, MBP-1, ENO1L1, ENO1, Alpha-Enolase, Enolase-Alpha, 2-phospho-D-glycerate hydro-lyase, Non-neural enolase, Enolase 1, MPB-1, Phosphopyruvate hydratase, C-myc promoter-binding protein, Plasminogen-binding protein, MBPB1.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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