The ENKD1 Polyclonal Antibody (PAC040782) is a valuable tool for researchers studying ENKD1, a protein involved in various cellular processes, including gene expression regulation and cell signaling. Raised in rabbits, this antibody is specifically designed for use in Western blot applications and is highly reactive with human samples. By binding to the ENKD1 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential component for studies in molecular biology and cell biology.
ENKD1, also known as a transcriptional regulator, plays a crucial role in gene expression regulation and is implicated in various cellular functions. Understanding the function and activity of ENKD1 can provide insights into key biological processes and potentially lead to the development of novel therapies for diseases related to gene dysregulation. This antibody is an invaluable tool for researchers looking to uncover the role of ENKD1 in health and disease.
Western blot. All lanes: ENKD1 antibody at 7µg/ml + Mouse brain tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 39, 26 kDa. Observed band size: 26 kDa.
Immunohistochemistry of paraffin-embedded human testis tissue using PACO40782 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO40782 at dilution of 1:100.
Background:
cytoplasmic microtubule, microtubule cytoskeleton
Synonyms:
Enkurin domain-containing protein 1, ENKD1, C16orf48
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The canonical protein encoded by this gene has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This gene is expressed in many tissues but has its highest expression in heart and skeletal muscle. It is expressed in the retinal neuroepithelium and lens epithelium in the developing murine eye and haploinsufficiency of this gene in humans and zebrafish is associated with microphthalmia. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2017]
