The Endoplasmin Polyclonal Antibody (CAB0989) is a powerful tool for researchers studying endoplasmin, a chaperone protein involved in protein folding and quality control in the endoplasmic reticulum. This antibody, generated in rabbits, exhibits high specificity for endoplasmin in human samples and has been validated for use in Western blotting applications.Endoplasmin, also known as HSP90B1, plays a crucial role in maintaining cellular homeostasis by assisting in the folding and maturation of client proteins. Dysregulation of endoplasmin function has been linked to various diseases, making it a promising target for therapeutic interventions.
By utilizing the Endoplasmin Polyclonal Antibody, researchers can effectively detect and analyze endoplasmin levels in different cell types, providing valuable insights into protein folding mechanisms and their implications in disease development. This antibody is an essential tool for studies in molecular biology, cell biology, and protein quality control research.Unlock the potential of your research with the Endoplasmin Polyclonal Antibody (CAB0989) and gain a deeper understanding of endoplasmin's role in cellular function and disease pathways.
Product Name:
HSP90B1 Rabbit Polyclonal Antibody
SKU:
CAB0989
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 40-310 of human Grp94 (NP_003290.1).
This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15.
Purification Method:
Affinity purification
Gene ID:
7184
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded rat testis using Grp94 Rabbit pAb (CAB0989) at dilution of 1:200 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
