The Endophilin A3 Polyclonal Antibody (CAB4112) is a valuable tool for researchers studying the role of Endophilin A3 in cellular processes. Endophilin A3 is a protein involved in membrane trafficking and has been shown to play a role in synaptic vesicle endocytosis and neuronal development.This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to Endophilin A3, researchers can detect and analyze the protein in various cell types, allowing for in-depth studies in neuroscience and cell biology.
The importance of understanding the function of Endophilin A3 extends to research on neurological disorders, such as Alzheimer's disease and Parkinson's disease, where abnormalities in membrane trafficking processes have been implicated. By elucidating the role of Endophilin A3, researchers may uncover novel therapeutic targets for these challenging conditions.
Product Name:
SH3GL3 Rabbit Polyclonal Antibody
SKU:
CAB4112
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human SH3GL3 (NP_003018.3).
Cytoplasm, Early endosome membrane, Peripheral membrane protein.
Calculated MW:
39kDa
Observed MW:
39kDa
Enables identical protein binding activity. Predicted to be involved in synaptic vesicle uncoating. Predicted to be located in acrosomal vesicle; early endosome membrane; and presynapse. Predicted to be part of early endosome. Predicted to be active in glutamatergic synapse; postsynaptic density, intracellular component; and postsynaptic endosome.
Purification Method:
Affinity purification
Gene ID:
6457
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SH3GL3 antibody (CAB4112) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
