The Endophilin A2 Polyclonal Antibody (CAB7449) is a valuable tool for research involving the Endophilin A2 protein, which plays a key role in membrane trafficking and endocytosis processes within cells. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.Endophilin A2 is a protein involved in the formation of vesicles that transport molecules within cells, making it essential for various cellular processes including synaptic vesicle recycling and protein trafficking. Research on Endophilin A2 is important for understanding how cells regulate their internal environment and communicate with other cells through vesicle transport mechanisms.
This antibody enables precise detection and analysis of Endophilin A2 in different cell types, making it a valuable tool for studies in cell biology, neuroscience, and cancer research. By targeting Endophilin A2, researchers can gain insights into the mechanisms underlying cellular communication and potentially uncover new therapeutic targets for diseases related to abnormal membrane trafficking processes.
Product Name:
SH3GL1 Rabbit Polyclonal Antibody
SKU:
CAB7449
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat,Monkey
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 219-368 of human SH3GL1 (NP_003016.1).
Cell projection, Cytoplasm, Early endosome membrane, Peripheral membrane protein, podosome.
Calculated MW:
41kDa
Observed MW:
41kDa
This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
6455
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of COS-7 cells, using SH3GL1 antibody (CAB7449) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
