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Anti-SH3GL2 Antibody (CAB5701)

SKU:
CAB5701
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 9 Anti-SH3GL2 Antibody CAB5701
  • Cell Biology Antibodies 9 Anti-SH3GL2 Antibody CAB5701
€139 - €419
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Description

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Antibody Name:Anti-SH3GL2 Antibody
Antibody SKU:CAB5701
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human SH3GL2 (NP_003017.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse
Positive Samples:HeLa, BT-474, 293T, HepG2, Mouse brain, Mouse testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human SH3GL2 (NP_003017.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MSVA GLKK QFHK ATQK VSEK VGGA EGTK LDDD FKEM ERKV DVTS RAVM EIMT KTIE YLQP NPAS RAKL SMIN TMSK IRGQ EKGP GYPQ AEAL LAEA MLKF GREL GDDC NFGP ALGE VGEA MREL SEVK DSLD IEVK QNFI DPLQ NLHD KDLR EIQH HLKK LEGR RLDF DYKK KRQG KIPD EELR QALE KFDE SKEI AESS MFNL LEMD IEQV SQLS ALVQ AQLE YHKQ AVQI LQQV TVRL EERI RQAS SQPR REYQ PKPR MSLE FPTG DS
Gene ID:6456
Uniprot:Q99962
Cellular Location:Cytoplasm, Membrane, Peripheral membrane protein
Calculated MW:39kDa
Observed MW:38kDa/40kDa
Synonyms:SH3GL2, CNSA2, EEN-B1, SH3D2A, SH3P4
Background:
UniProt Protein Function:endophilin 1: Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Belongs to the endophilin family.
UniProt Protein Details:

Protein type:Adaptor/scaffold; Membrane protein, peripheral; Vesicle

Chromosomal Location of Human Ortholog: 9p22

Cellular Component: cytosol; Golgi membrane; plasma membrane

Molecular Function:identical protein binding; protein binding

Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; central nervous system development; microtubule-based movement; negative regulation of epidermal growth factor receptor signaling pathway; signal transduction

UniProt Code:Q99962
NCBI GenInfo Identifier:10720276
NCBI Gene ID:6456
NCBI Accession:Q99962.1
UniProt Secondary Accession:Q99962,Q9NQK5, B2R618,
UniProt Related Accession:Q99962
Molecular Weight:39,962 Da
NCBI Full Name:Endophilin-A1
NCBI Synonym Full Names:SH3 domain containing GRB2 like 2, endophilin A1
NCBI Official Symbol:SH3GL2  
NCBI Official Synonym Symbols:CNSA2; SH3P4; EEN-B1; SH3D2A  
NCBI Protein Information:endophilin-A1
UniProt Protein Name:Endophilin-A1
UniProt Synonym Protein Names:EEN-B1; Endophilin-1; SH3 domain protein 2A; SH3 domain-containing GRB2-like protein 2
Protein Family:Endophilin
UniProt Gene Name:SH3GL2  
UniProt Entry Name:SH3G2_HUMAN
Anti-SH3GL2 Antibody (CAB5701)Western blot analysis of extracts of various cell lines, using SH3GL2 antibody (CAB5701) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
Anti-SH3GL2 Antibody (CAB5701)Immunofluorescence analysis of HeLa cells using SH3GL2 antibody (CAB5701). Blue: DAPI for nuclear staining.

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