The Endomucin Polyclonal Antibody (CAB8494) is a valuable tool for researchers studying endomucin, a cell surface protein involved in endothelial cell function and blood vessel development. This antibody, produced in rabbits, is highly specific to human endomucin and is suitable for use in various applications, including immunohistochemistry and flow cytometry.Endomucin is known for its role in maintaining vascular integrity and regulating angiogenesis, making it a key target in studies of vascular biology and cardiovascular diseases. By targeting endomucin with this antibody, researchers can accurately detect and analyze the protein in different cell types and tissue samples, providing valuable insights into its function and potential therapeutic applications.
The Endomucin Polyclonal Antibody (CAB8494) is an essential tool for researchers seeking to deepen their understanding of endomucin's role in vascular biology and its potential implications for disease development and treatment strategies. Its high specificity and versatility in various experimental settings make it a valuable asset for studies aimed at unraveling the complex mechanisms underlying endothelial cell function and blood vessel formation.
Product Name:
EMCN Rabbit Polyclonal Antibody
SKU:
CAB8494
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 19-135 of human Endomucin (NP_057326.2).
Cell membrane, Membrane, Secreted, Single-pass type I membrane protein, Single-pass type I membrane protein.
Calculated MW:
27kDa
Observed MW:
35kDa
EMCN is a mucin-like sialoglycoprotein that interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix (Kinoshita et al., 2001 [PubMed 11418125]).
Purification Method:
Affinity purification
Gene ID:
51705
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Endomucin antibody (CAB8494) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
