CD105 Rabbit Polyclonal Antibody (CAB5639)
- SKU:
- CAB5639
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cardiovascular
Frequently bought together:
Description
Product Name: | CD105 Rabbit Polyclonal Antibody |
SKU: | CAB5639 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-337 of human CD105/Endoglin (NP_001108225.1). |
Sequence: | ETVH CDLQ PVGP ERGE VTYT TSQV SKGC VAQA PNAI LEVH VLFL EFPT GPSQ LELT LQAS KQNG TWPR EVLL VLSV NSSV FLHL QALG IPLH LAYN SSLV TFQE PPGV NTTE LPSF PKTQ ILEW AAER GPIT SAAE LNDP QSIL LRLG QAQG SLSF CMLE ASQD MGRT LEWR PRTP ALVR GCHL EGVA GHKE AHIL RVLP GHSA GPRT VTVK VELS CAPG DLDA VLIL QGPP YVSW LIDA NHNM QIWT TGEY SFKI FPEK NIRG FKLP DTPQ GLLG EARM LNAS IVAS FVEL PLAS IVSL HASS CGGR LQTS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | END; HHT1; ORW1; CD105/Endoglin |
Positive Sample: | bewo,HUVEC,HAP1 |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 71kDa |
Observed MW: | 100kDa |
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 2022 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |