The Endo-G Rabbit Monoclonal Antibody (CAB8801) is a powerful tool for researchers studying Endoglin, a cell surface glycoprotein involved in various biological processes such as angiogenesis and tissue remodeling. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for use in a variety of research applications including immunohistochemistry and flow cytometry.Endoglin is a key player in TGF-beta signaling pathways, regulating cell proliferation, migration, and differentiation. Dysregulation of Endoglin has been implicated in various diseases including cancer, cardiovascular disorders, and hereditary hemorrhagic telangiectasia.
The Endo-G Rabbit Monoclonal Antibody enables precise detection and analysis of Endoglin expression in different cell types, providing valuable insights into its role in disease progression and potential therapeutic targets.By utilizing the Endo-G Rabbit Monoclonal Antibody (CAB8801), researchers can deepen their understanding of Endoglin's function and explore its impact on disease pathology. This antibody is a valuable asset for studies in vascular biology, oncology, and related fields, offering reliable and accurate results to drive scientific discovery and advancements in clinical research.
Product Name:
Endo G Rabbit Monoclonal Antibody
SKU:
CAB8801
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 198-297 of human Endo G (Q14249).
The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.
Purification Method:
Affinity purification
Gene ID:
2021
Clone Number:
ARC1308
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Endo G Rabbit mAb (CAB8801) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
