The ENAH Polyclonal Antibody (CAB17932) is a valuable tool for researchers studying the ENAH protein, which is involved in cell migration and actin dynamics. This rabbit-derived antibody is highly specific to human ENAH samples and is validated for use in Western blot applications. By binding to the ENAH protein, this antibody enables the detection and analysis of ENAH in various cell types, making it ideal for studies in cell biology, cancer research, and developmental biology.
ENAH, also known as Mena, is a key player in regulating cell motility and invasion, making it a critical target for research in metastasis and cancer progression. Its role in cytoskeletal dynamics and cellular signaling pathways also suggests its involvement in cell growth and differentiation. Understanding the function of ENAH is essential for uncovering its potential as a therapeutic target in cancer treatment and other related fields.
Product Name:
ENAH Rabbit Polyclonal Antibody
SKU:
CAB17932
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 412-591 of human ENAH (NP_001008493.1).
This gene encodes a member of the enabled/ vasodilator-stimulated phosphoprotein. Members of this gene family are involved in actin-based motility. This protein is involved in regulating the assembly of actin filaments and modulates cell adhesion and motility. Alternate splice variants of this gene have been correlated with tumor invasiveness in certain tissues and these variants may serve as prognostic markers. A pseudogene of this gene is found on chromosome 3.
Purification Method:
Affinity purification
Gene ID:
55740
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ENAH Rabbit pAb (CAB17932) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
