EN2 Rabbit Polyclonal Antibody (CAB17480)
- SKU:
- CAB17480
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | EN2 Rabbit Polyclonal Antibody |
SKU: | CAB17480 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-333 of human EN2 (NP_001418.2). |
Sequence: | AFTA EQLQ RLKA EFQT NRYL TEQR RQSL AQEL SLNE SQIK IWFQ NKRA KIKK ATGN KNTL AVHL MAQG LYNH STTA KEGK SDSE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | EN2 |
Positive Sample: | U-87MG,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | fibrillar center, nucleolus, nucleoplasm, nucleus |
Calculated MW: | 34kDa |
Observed MW: | 33kDa |
Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.
Purification Method: | Affinity purification |
Gene ID: | 2020 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |