The EMR1 Polyclonal Antibody (CAB1256) is a highly specialized research tool designed for the study of EMR1, a cell surface molecule involved in immune regulation. This antibody, generated in rabbits, exhibits high reactivity towards human samples and has been validated for use in Western blot applications. By specifically binding to the EMR1 protein, researchers can accurately detect and analyze its expression in various cell types, making it an invaluable tool for investigations in immunology and cancer research.EMR1, also known as EGF-like module-containing mucin-like hormone receptor-like 1, plays a crucial role in immune modulation by regulating inflammatory responses and potentially influencing allergic reactions.
Its role in immune function modulation makes it a promising target for research in diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the functions of EMR1 is essential for the development of effective therapies that can either enhance or suppress immune responses in these disease contexts.Get your hands on the EMR1 Polyclonal Antibody (CAB1256) today and unlock new insights into the intricate mechanisms of immune regulation and disease pathogenesis. With its high specificity and sensitivity, this antibody is a must-have tool for any researcher exploring the complexities of the immune system.
Product Name:
EMR1 Rabbit Polyclonal Antibody
SKU:
CAB1256
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 477-596 of human EMR1 (NP_001965.3).
This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2015
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of Mouse lung, using EMR1 antibody (CAB1256) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
