EMP3 Antibody (PACO26469)
- SKU:
- PACO26469
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
EMP3 Antibody (PACO26469)
The EMMPRIN Polyclonal Antibody (PAC026469) is a valuable tool for research involving EMMPRIN, a cell surface glycoprotein involved in several physiological and pathological processes, including tumor progression and immune responses. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in applications such as Western blotting. By binding to the EMMPRIN protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in cancer biology and immunology.
EMMPRIN, also known as CD147, is a multifunctional molecule that contributes to cell migration, invasion, and angiogenesis, making it a promising target for cancer therapy and research. Its involvement in regulating immune responses further underscores its importance in diseases such as cancer and autoimmune disorders. By studying the activity of EMMPRIN, researchers can gain valuable insights into the mechanisms underlying tumor development and immune modulation, paving the way for the development of novel therapeutic strategies.
| Antibody Name: | EMP3 Antibody (PACO26469) |
| Antibody SKU: | PACO26469 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IF:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Epithelial membrane protein 3 protein (25-65AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescent analysis of Hela cells using PACO26469 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Western Blot All lanes: EMP3 antibody at 3µg/ml + Mouse heart tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 19 kDa Observed band size: 19, 31 kDa . |
| Background: | Probably involved in cell proliferation and cell-cell interactions. |
| Synonyms: | Epithelial membrane protein 3 (EMP-3) (Hematopoietic neural membrane protein 1) (HNMP-1) (Protein YMP), EMP3, YMP |
| UniProt Protein Function: | EMP3: Probably involved in cell proliferation and cell-cell interactions. Belongs to the PMP-22/EMP/MP20 family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 19q13.33 Cellular Component: plasma membrane Molecular Function:protein binding Biological Process: bleb formation; cell death; negative regulation of cell proliferation |
| NCBI Summary: | The protein encoded by this gene belongs to the PMP-22/EMP/MP20 family of proteins. The protein contains four transmembrane domains and two N-linked glycosylation sites. It is thought to be involved in cell proliferation, cell-cell interactions and function as a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
| UniProt Code: | P54852 |
| NCBI GenInfo Identifier: | 1706644 |
| NCBI Gene ID: | 2014 |
| NCBI Accession: | P54852.1 |
| UniProt Secondary Accession: | P54852,Q6FH01, |
| UniProt Related Accession: | P54852 |
| Molecular Weight: | 18,429 Da |
| NCBI Full Name: | Epithelial membrane protein 3 |
| NCBI Synonym Full Names: | epithelial membrane protein 3 |
| NCBI Official Symbol: | EMP3Â Â |
| NCBI Official Synonym Symbols: | YMPÂ Â |
| NCBI Protein Information: | epithelial membrane protein 3 |
| UniProt Protein Name: | Epithelial membrane protein 3 |
| UniProt Synonym Protein Names: | Hematopoietic neural membrane protein 1; HNMP-1; Protein YMP |
| Protein Family: | Epithelial membrane protein |
| UniProt Gene Name: | EMP3Â Â |
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