The EMG1 Polyclonal Antibody (CAB4421) is a valuable tool for researchers studying the EMG1 protein, a key player in ribosome biogenesis and RNA processing. This antibody, derived from rabbits, exhibits high specificity and sensitivity in detecting EMG1 in human samples, making it an essential component in Western blot assays.EMG1 is essential for the maturation of the small ribosomal subunit and is known to be involved in various cellular processes, including mRNA splicing and translation.
Dysregulation of EMG1 has been linked to cancer and other diseases, making it a promising target for therapeutic interventions.By accurately detecting and analyzing EMG1 expression, researchers can gain insights into the role of this protein in cellular function and disease pathology. The EMG1 Polyclonal Antibody is a reliable tool for investigating the intricate mechanisms of ribosome biogenesis and RNA processing, with potential applications in cancer research and drug development.
Product Name:
EMG1 Rabbit Polyclonal Antibody
SKU:
CAB4421
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-244 of human EMG1 (NP_006322.4).
This gene encodes an essential, conserved eukaryotic protein that methylates pseudouridine in 18S rRNA. The related protein in yeast is a component of the small subunit processome and is essential for biogenesis of the ribosomal 40S subunit. A mutation in this gene has been associated with Bowen-Conradi syndrome. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10436
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using EMG1 antibody (CAB4421) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
