The Emerin Rabbit Monoclonal Antibody (CAB4187) is a high-quality antibody specifically designed for research involving the Emerin protein. Emerin is a key component of the nuclear envelope and plays a critical role in various cellular processes, including nuclear structure maintenance and gene regulation.This antibody is generated from rabbits and has been extensively validated for use in various applications, including Western blot and immunofluorescence. It binds specifically to the Emerin protein, enabling accurate detection and analysis in a wide range of cell types.
Studies have shown that abnormalities in the Emerin protein are associated with various diseases, including Emery-Dreifuss muscular dystrophy and certain forms of cancer. By utilizing the Emerin Rabbit Monoclonal Antibody, researchers can gain valuable insights into the function and regulation of this important protein, advancing our understanding of its role in health and disease.
Product Name:
Emerin/EMD Rabbit Monoclonal Antibody
SKU:
CAB4187
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-254 of human Emerin/EMD (P50402).
Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene.
Purification Method:
Affinity purification
Gene ID:
2010
Clone Number:
ARC0921
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Emerin/EMD Rabbit mAb (CAB4187) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
